Characteristics of nondepolarizing neuromuscular block: (I) post-junctional block by alpha-bungarotoxin
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منابع مشابه
Characteristics of nondepolarizing neuromuscular block: (I) post-junctional block by alpha-bungarotoxin.
The characteristics of neuromuscular block produced by alpha-bungarotoxin, a post-junctionally active polypeptide toxin purified from snake venoms, have been studied in vivo in 12 anaesthetized cats, using the sciatic nerve-tibialis anterior muscle preparation. The onset of the neuromuscular block was slow and without fasciculation. The block was persitently progressive. The time course of the ...
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Descriptions of the South American arrow poisons known as curares were reported by explorers in the 16th century, and their site of action in producing neuromuscular block was determined by Claude Bernard in the mid-19th century. Tubocurarine, the most important curare alkaloid, played a large part in experiments to determine the role of acetylcholine in neuromuscular transmission, but it was n...
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The antagonism of the nondepolarizing neuromuscular blockade is accomplished many times in a given day. Fortunately, the incidents of complications are low. If they do occur and are not recognized and treated properly, however, the results can be serious. In this article, the author reviews the curariform group of drugs, anticholinesterases, and anticholinergics, evaluating the antagonism of th...
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ژورنال
عنوان ژورنال: Canadian Anaesthetists’ Society Journal
سال: 1977
ISSN: 0008-2856,1496-8975
DOI: 10.1007/bf03006234